Two goals in two second half minutes from the visitors condemned Rangers to a 2-1 defeat in W12.
Clint Hill and R's nemesis Clinton Morrison struck midway through the half, to send the Hoops to the foot of the Championship table.
Earlier, Damion Stewart gave Rangers the initiative with his second goal of the campaign, heading home Akos Buzsaky's tenth minute corner.
But in truth, Palace were good value for their victory in the second half, as Rangers' poor form continued.
Luigi De Canio welcomed Zesh Rehman back to the starting XI at the expense of Adam Bolder.
Seventeen year-old striker Angelo Balanta was named amongst the R's substitutes for the first time, after impressing for the Reserves six days ago.
Palace boss Neil Warnock made a solitary change of his own too, bringing in Danny Butterfield, at the expense of the suspended Matt Lawrence.
After Franck Songo'o's saw his first minute effort easily gathered at his near post by Lee Camp, Rangers took a tenth minute lead.
Buzsaky's out-swinging corner was flighted to the edge of the six-yard box and Stewart rose unchallenged to head past the exposed Palace custodian Julian Speroni.
Palace skipper Mark Hudson nearly levelled matter two minutes later though, heading a yard over the bar after Rangers were caught sleeping at the back.
But it was the hosts who could've been two ahead on the quarter hour, when Rowlands played a long ball into the path of Ben Sahar.
With Hudson back-pedalling, Sahar looked up and spotted the on-rushing Rowan Vine, who saw his first time effort clawed to safety by Speroni.
The Palace stopper - whose goalkeeping heroics denied Rangers all three points in SE25 three weeks ago - was in inspired form again moments later, making a superb double save to deny Scott Sinclair and then Vine, as the R's forced the initiative.
It was fast becoming the Julian Speroni show yet again, as the Argentinean pulled off yet another fine point-blank save to thwart Sahar midway through the half.
Ben Watson's teasing right footed free-kick flew inches wide of Camp's left hand post on the half hour, before the same player was again denied by the R's number one, this time from a direct 20-yard set-piece.
Palace made a change at the break, with Lee Hills replacing Jose Fonte - resulting in a defensive reshuffle at the heart of the Eagles defence.
It was referee Alan Wiley who took centre stage at the start of the second period though, as he made one poor decision after another, to the disgust of the Rangers faithful.
Watson's deliveries had caused Rangers problems all evening and it was the Palace midfielder who created their equaliser in the 65th minute.
Stewart was harshly penalised for a foul on Scowcroft and Hill applied the all-important touch to Watson's centre, prodding the ball past Camp from eight yards.
Buoyed by their goal, Palace marched into a 2-1 lead 60 seconds later, as Morrison notched from close range after Hudson's header rebounded off the bar.
The Eagles were at their free-flowing best by now and after substitute Sean Scannell left Chris Barker for dead with a run from deep inside his own half, Lee Hills headed over with the goal at his mercy.
In a last throw of the dice, De Canio threw on teenager Balanta and Bolder, but it mattered little, as Rangers - despite the late dismissal of Palace gaffer Warnock for his involvement in a touchline skirmish - suffered more home heartache.
QPR: Camp, Barker, Stewart, Buzsaky (Bolder 86), Rowlands (Nygaard 72), Sahar (Balanta 84), Malcolm, Vine, Rehman, Leigertwood, Sinclair.
Subs: Cole, Ainsworth.
Scorers: Stewart 10
Bookings: Rowlands 49, Rehman 78, Camp 91
Crystal Palace: Speroni, Hill, Hudson, Scowcroft, Morrison, Watson, Soares (Fletcher 73), Butterfield, Fonte (Hills 46), Songo'o (Scannell 60), Derry.
Subs: Freedman, Martin.
Scorers: Hill 65, Morrison 67
Bookings: Butterfield 46
Referee: Mr A G Wiley
Attendance:
